Nucleic Acid Extraction
Magnetic bead–based workflows enable genomic DNA extraction from a wide range of sample types without centrifugation, simplifying handling and allowing seamless scaling from manual processing to automation.
Genomic DNA extraction
Magnetic bead technology for automated genomic DNA extraction
Genomic DNA extraction workflows often rely on spin columns and centrifugation, which can complicate automation. Magnetic bead-based workflows use magnetic separation instead of centrifugation, enabling automated genomic DNA extraction with reduced manual handling while maintaining consistent DNA purities and yields.
Integrated solutions for automated magnetic bead DNA extraction:
- Extraction kit – Clean Blood & Tissue DNA Kit
- Magnetic stand – HEATMAG module for temperature-controlled bead capture and separation, optimizing sample lysis and elution
- Liquid handling platform – ASSIST PLUS pipetting robot for automating repetitive pipetting steps
Magnetic bead-based extraction kit | |
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Clean Blood & Tissue DNA Kit | |
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| Magnetic bead-based genomic DNA extraction kit | |
| To the product page | |
| Application | gDNA extraction |
| Starting material | Blood (citrate, EDTA), buffy coat, tissue (up to 10 mg), cultured cells (up to 25 µg gDNA from 5×106 cells) |
| Recommended input volume | 200-250 µl |
| Throughput | Up to 24 samples on the ASSIST PLUS |
| Intended use | Research use only |
| Elution volume | 120 µl or higher (using the ASSIST PLUS with HEATMAG in tube adapter configuration) |
| Typical recovery | 5-7 µg |
| Processing mode | Automated and manual |
| Downstream application | PCR, qPCR, NGS, Sanger sequencing, enzymatic reactions |
| Unit size | 16, 96 or 384 preps |
| Storage | Proteinase K and magnetic beads 2-8°C, other reagents 15-25°C (RT) |
| Note | Includes proteinase K (20 mg/ml) |
