MIRO CANVAS Fully automated NGS sample prep

MIRO CANVAS uses digital microfluidics to perform sample preparation steps within the singe-use MIRO cartridge. Sample and reagents are pipetted into the cartridge, and the microfluidics system automatically performs steps required for sample and library preparation, without user intervention, to produce samples for sequencing.

• MIRO technology

  MIRO technology uses electromechanical forces to move droplets over an array of electrodes. The electrode board has four thermal and four magnetic zones so that thermal cycling and magnetic bead operations can be performed automatically. Droplets move within the cartridge and are surrounded by air. The microfluidics technology also enables reduction of volumes for reduced running costs.

• MIRO cartridge

  The system uses MIRO cartridges, which are compatible with all commonly used reagents for sample preparation and enable easy experimental set-up. It is electronics-free, and incorporates microfluidic channels that sit in a layer above an open electrowetting plane, where the movement of droplets is controlled digitally by the electrodes that the cartridge sits upon.

• Full walk-away automation

  The system integrates steps necessary to perform sample preparation, including thermal cycling and magnetic bead operations, to minimize hands-on time and provide complete walkaway automation. The system senses reactions during the run, and ensures that all reagents and processes follow the same protocol from day to day, or site to site.

• Simple run set-up

  The onboard touchscreen on the MIRO CANVAS guides the user through setting up the run in minutes. The system also senses when a reagent has been loaded, and prompts the user to move onto the next step.

• Long DNA Fragments

  The microfluidics technology used in MIRO CANVAS provides a gentle environment and is favorable to long DNA fragments.