Clean Blood & Tissue DNA Kit Magnetic bead-based genomic DNA extraction kit

How it works

The Clean Blood & Tissue DNA Kit follows a 4 step workflow from sample to purified gDNA.

• Overview

  1. Lysis: The sample is treated with a lysis buffer to break open cells, release nucleic acids and denature proteins and other impurities. Heating optimizes sample lysis.
  2. Binding: Magnetic beads are added to the lysate, where gDNA selectively binds to the bead surface in the presence of a binding buffer.
  3. Washing: Several wash steps remove proteins, salts and other contaminants, ensuring high gDNA purity.
  4. Elution: The purified gDNA is released from the magnetic beads into an elution buffer, ready for downstream use. Heating enhances sample elution.

• High yield, high purity gDNA

  The Clean Blood & Tissue DNA Kit delivers high genomic DNA yields from blood with consistent purity, as indicated by A260/280 and A260/230 ratios. The resulting gDNA is suitable for downstream applications such as (q)PCR and NGS. Read the full application note.

• Compatible sample types

  Use Clean Blood & Tissue DNA Kit with:

  • Blood (citrate, EDTA)
  • Buffy coat
  • Tissue samples (up to 10 mg)
  • Cultured cells (up to 25 µg gDNA from 5×10⁶ cells) 

  This versatility makes the Clean Blood & Tissue DNA Kit well suited to genomic studies, clinical research and other applications where high quality DNA is essential.

• Save time and boost performance 

  In head-to-head testing with whole blood, the Clean Blood & Tissue DNA Kit produced higher purity genomic DNA than a leading spin column method, with comparable DNA yields and significantly reduced hands-on time (~5 minutes automated vs. 40–50 minutes manual). 

  View comparison poster

• Integration with HEATMAG module

  The Clean Blood & Tissue DNA Kit works with INTEGRA's HEATMAG module, a magnetic stand that captures magnetic beads during binding and washing steps in bead-based workflows. 

  The HEATMAG also offers integrated heating – up to 65 °C – to enhance lysis and elution, helping to improve DNA yields. It is compatible with standard microcentrifuge tubes and 96 well PCR plates.

• Integration with our pipetting platforms

  Combine the Clean Blood & Tissue DNA Kit with the HEATMAG module and ASSIST PLUS pipetting robot for automated workflows: 

  The ASSIST PLUS pipetting robot:

  • Ideal for variable sample numbers
  • Offers hands-free processing
  • Provides intuitive, user-friendly programming
  • Optimized pipetting protocols to process up to 24 samples that can be easily modified to accommodate differing input and output volumes