At INTEGRA, we are committed to finding eco-friendly solutions and listening to our customer feedback to ensure we deliver high quality pipette tips that can improve pipetting performance and results in the lab. This is why we have bridged the gap to make it possible for you to order many of our specialty GRIPTIPS in ECO Racks. These racks contain 60 % less plastic, while maintaining the high standards that you expect from INTEGRA products, and are now available for 300 and 1250 μl WIDE BORE, 300 µl LONG and 1250 µl SHORT GRIPTIPS – as well as 12.5, 125, 300 and 1250 μl Low Retention options. The ECO Racks can also be paired with our one-of-a-kind, reusable PopTop Base for the most convenient pipetting experience.
Tips to fit your needs
High quality pipettes and correct techniques are essential to ensure reliable and reproducible results, but the choice of pipette tip is often overlooked. We understand that there isn’t one tip for every application, which is why we offer a variety of options alongside our standard GRIPTIPS to match the needs of specific laboratory workflows. For example, the 300 µl LONG GRIPTIPS are 102 mm in length, allowing access to 100 mm or 1.4 ml tubes without the concern of contaminating the pipette shaft. At the other end of the scale, the 1250 µl SHORT GRIPTIPS enable users to pipette closer to the workbench, improving pipetting ergonomics for repeated high-volume pipetting tasks.
Wide bore options
Wide bore tips are commonly used in cell culture workflows to reduce the shearing forces. Many steps in these protocols – such as cell detachment, sampling, seeding and cell-based assays – require mixing with a pipette, which can cause trauma to cells as they are repeatedly forced through the narrow orifice at the end of the tip. This can impact cell viability, spreading and proliferation, decreasing the reproducibility of results. Our 300 and 1250 μl WIDE BORE GRIPTIPS have a larger aperture – with an inner diameter of 1.5 mm – to alleviate these shearing forces, helping to improve the consistency of cell-based applications.
Cell culture isn’t the only pipetting task that can benefit from the use of wide bore tips. These tips can also be used to reduce flow resistance when pipetting some non-aqueous solutions. For example, they allow very viscous solutions – e.g. 80 % glycerol – to enter the tip more easily and can reduce foaming when dispensing washing agents such as Tween® 20.
Low retention tips
Another consideration when choosing the right pipette tip is the physiochemical properties of the liquid. This can also have a significant impact on accuracy and precision, particularly at low volumes. Using standard pipette tips made of polypropylene to pipette low surface tension liquids – such as oils or solutions containing detergents – or viscous fluids common in some biological applications can cause the tips to take on hydrophilic properties, resulting in fluid retention as the sample adheres to the inner surface of the tip. Low Retention GRIPTIPS – developed to work with our range of manual and electronic pipettes – offer an ideal solution to overcome this issue. Incorporating a unique polypropylene blend with increased hydrophobic properties, Low Retention GRIPTIPS ensure optimal liquid recovery to enhance the reproducibility of research results. We chose this blended polypropylene approach over the silicone coating techniques commonly used for low retention disposable tips as it prevents residues washing or leaching out with the sample and negatively impacting results.
Designed for the perfect fit
The new ECO Rack options, like all GripTips, do not require excessive attachment and ejection forces – unlike universal pipette tips. The rim of the GRIPTIP snaps over the lobes of the pipette, and the high lateral resistance ensures firm attachment and perfect alignment. The shoulder provides a positive stop to prevent over-tightening of the tip, meaning it can only be attached at that precise point and no further – the tip is either on or off. This design combats the common problem of leaking tips, or even tips completely falling off the pipette, regardless of how many side wall touch offs are performed.