INTEGRA MAG Modules - MAG and HEATMAG

MAG and HEATMAG Streamlining magnetic bead purifications

Streamlining magnetic bead purifications

Product story

We have introduced the MAG and HEATMAG modules with you, the scientists, in mind. These cutting-edge solutions streamline magnetic bead purification in a broad range of molecular and proteomics workflows. The powerful magnets ensure fast bead collection with minimal loss and carryover, and their adjustable height can be customized to your volume requirements for optimal results every time. But that's not all; the HEATMAG module goes one step further by combining magnetic separation with heating capabilities, providing the perfect setting for nucleic acid extraction. It's a truly unique solution that sets INTEGRA apart from the rest.

The MAG and HEATMAG modules offer versatility like never before; they can be seamlessly integrated with our pipetting platforms for semi or fully automated workflows, or used as standalone units for manual processing, depending on your requirements. Combining them with the VIAFLO 96,  MINI 96 or VIAFLO 384 pipetting platforms will enable you to process 96 or 384 well plates, or 24 tubes, simultaneously, significantly boosting your productivity. With the ASSIST PLUS pipetting robot, the MAG and HEATMAG modules provide full walk-away magnetic bead purification without the need for costly grippers and robotic arms. This combination opens up new possibilities for your laboratory, making it easier than ever to achieve high quality results.

In summary, the key benefits of the MAG and HEATMAG modules are:

  • Adjustable magnet heights for bead collection, depending on the volume.
  • Exceptional magnet strength, ensuring minimal bead carryover and maximum yields.
  • HEATMAG offers a unique combination of magnetic engagement and heating capabilities for lysis or elution.
  • Easy integration with the VIAFLO 96, MINI 96 or VIAFLO 384 pipetting platforms.
  • Full automation when combined with the ASSIST PLUS pipetting robot.
How it Works

How it works

MAG modules enable automated bead collection using hands-free vertical magnet movement.

  • Overview

    Overview of the HEATMAG module on an ASSIST PLUS
    1. Strong magnet for minimal bead loss. The magnetic array can be exchanged on the MAG modules.
    2. Automated bead collection using vertical magnet movement.
    3. Different labware formats, such as tubes or plates, can be processed.
    4. Magnetic bead purification workflows can be fully automated using the ASSIST PLUS pipetting robot.

     

  • Fast bead capture

    Top shot of a PCR adapter with magnets engaged

    Hands-free vertical movement of a strong magnetic array and adjustable bead collection height result in high yields. This enables automated bead collection and optimal magnetic bead capture at both low and high volumes.

    Users can switch between different preset heights when using it manually, or benefit from full workflow automation on the ASSIST PLUS pipetting robot.

  • Heating and magnetic separation in one

    the HEATMAG module with an heating icon

    HEATMAG combines magnets and heating in one device, supporting workflows at temperatures of up to 65 °C. This unique capability is crucial for tasks like lysis or elution

  • Versatility

    MAG Module and all compatible labware adapters

    The modules are compatible with a variety of labware types, providing added versatility for a wide range of applications.

  • Boost productivity for magnetic bead applications

    All INTEGRA instruments you can use with the MAG and HEATMAG modules

    Integration of MAG modules with the ASSIST PLUS pipetting robot allows fully automated, walk-away sample processing, optimizing workflow efficiency and boosting productivity in magnetic bead purification protocols.

    Combining the modules with the MINI 96, VIAFLO 96 or VIAFLO 384 enables the simultaneous processing of 96 or 384 wells, or 24 tubes, for high throughput magnetic bead clean-up.

  • Experience intuitive user interaction

    Experience intuitive user interaction

    Explore seamless automation with the ASSIST PLUS pipetting robot and VIALAB pipetting software, for effortless control of the MAG modules.To use the modules in combination with the MINI 96, VIAFLO 96, or VIAFLO 384, or on their own, simply connect them to a computer via a USB connection for easy customization, or install the Communication Module to enable Bluetooth communication with the MAG Control App on mobile devices.

Customer Voices

No reviews yet. Be the first to write one.

See it Work

See it work

Apps

Uses and Applications

Overview Applications Stories

Applications

PCR clean-up
PCR clean-up

PCR product purification using magnetic beads for efficient cleanup

Clean-up of reaction mixes after PCR protocols is essential to remove unincorporated primers or dNTPs, so that they do not disrupt subsequent reactions. The MAG module’s adapter for 96 or 384 well PCR plates enables hands-free PCR clean-ups for up to 384 simultaneous reactions per run.

MAG VIAFLO 384 in 3 position stage
NGS library clean-up
NGS library clean-up

Single-size and double size selection in NGS library preparation

Magnetic beads efficiently isolate DNA fragments based on their size, which is crucial for both single- and double-size selection in NGS library preparation. Magnetic bead purifications with the MAG modules, combined with the precision of INTEGRA's pipetting platforms, provide high yields with minimal bead loss.

MAG module PCR adapter on ASSIST PLUS
Nucleic acid extraction
Nucleic acid extraction

Magnetic beads simplify nucleic acid extraction, isolating DNA and RNA effectively

Isolation of nucleic acids requires selective binding of DNA or RNA from complex biological samples. Magnetic beads offer scalability in in nucleic acid extraction for both volumes and sample numbers. The bead collection height can be changed between the steps, allowing collection at optimal heights during binding/washing (volumes >500 µl) or elution steps (volumes <200 µl). In some extraction protocols, processing steps like lysis and elution require elevated temperatures; the combination of the HEATMAG module’s heating element with the adapter for 1.5 ml tubes is ideal for nucleic acid extractions.

MAG module on a VIAFLO 384 with 24 wells
Protein enrichment
Protein enrichment

Concentration of specific proteins in a biological sample using magnetic beads.

The surface of the magnetic beads can also be functionalized with specific ligands – e.g. antibodies for immunoprecipitations – for use in protein analysis. These ligands are chosen to have a high affinity for the target proteins of interest. Repetitive manual pipetting steps can be minimized by combining MAG modules with INTEGRA's pipetting platforms, providing more hands-free time.

HEATMAG module with a 1.5ml tube adapter on an ASSIST PLUS
Tech Info

Tech info

Find here a quick overview of the product specifications. More detailed information can be found in the download-section below.

Dimensions (W x D x H)
MAG: 13.3 x 7.3 x 8.9 cm (5.2 x 2.9 x 3.5 '') — HEATMAG: 13.3 x 7 x 8.9 cm (5.2 x 2.8 x 3.5 '')
Operating Conditions
Temperature: 5 to 40 °C — Humidity: <80 %
Weight
MAG: 1.0 kg (2.2 lbs) — HEATMAG: 1.1 kg (2.4 lbs)
Power Requirements
100-240 VAC, 50/60 Hz, device input: 24 V, 120 W
Downloads & More Parts and Numbers

Parts and numbers

Instrument
Instrument

MAG and HEATMAG modules

Description Part No.
MAG module for magnetic separation 4900
HEATMAG module for heating and magnetic separation 4901

 

Accessories
Accessories

Labware adapters and magnetic arrays

Description Part No.
Adapter for 1.5 ml tubes, 4 x 6 format (MAG / HEATMAG) 4905
Adapter for 96 well PCR plate (MAG /HEATMAG) 4906
Adapter and magnetic array for 384 well PCR plate (MAG) 4908
Pedestal (+50 mm) 4963

 

Recommended liquid handling instrument to access the tubes and wells

Labware Compatible modules Standalone use with VIAFLO and VOYAGER ASSIST PLUS with VIAFLO and VOYAGER VIAFLO 96 and VIAFLO 384 MINI 96
1.5 ml micro-centrifuge tubes MAG
HEATMAG
4 or 6 channel
VOYAGER
(10-1250 µl)
4 or 6 channel
VOYAGER
(10-1250 µl)
24 channel head
(10-1250 µl)
 
96 well
PCR plates
MAG
HEATMAG
8 or 12 channel 
VIAFLO/VOYAGER
(0.5-1250 µl)
8 or 12 channel 
VIAFLO/VOYAGER
(0.5-1250 µl)
96 channel head
(0.5-1250 µl)
MINI 96
all volumes
384 well
PCR plates
MAG 16 channel
VIAFLO
(0.5-125 µl)
16 channel
VIAFLO
(0.5-125 µl)
96 or 384 channel head
(0.5-125 µl)
 

 

-----

Control
Control

Software to adjust settings or run MAG and HEATMAG

Description Part No.
Communication module for MAG modules 4222
MAG Control for PC/laptop free download
MAG Control app for mobile devices

Apple App Store

Google Play Store

VIALAB more about VIALAB
VIALINK more about VIALINK

Download our MAG Control app for your mobile device:

Download the MAG CONTROL app for the MAG and HEATMAG modules

Download the MAG CONTROL app for the MAG and HEATMAG modules

ASSIST PLUS and D-ONE
ASSIST PLUS and D-ONE
VIAFLO and VOYAGER electronic pipettes
VIAFLO and VOYAGER electronic pipettes
96 channel electronic pipettes
96 channel electronic pipettes

Please visit MINI 96 and VIAFLO 96 and VIAFLO 384 electronic pipettes.