Pipette tips - aligned or as uneven as a mountain range?

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Pipette tips - aligned or as uneven as a mountain range?

Quite often, generic pipette tips on a multichannel pipette resemble a mountain range rather than perfectly aligned tips. The reason for misaligned tips lies in the widespread generic tip cone and tip fitting design as well as in the memory effect of the tip material, which gradually moves back to its original, non-stretched shape. Pipette tips not being perfectly level on a multichannel pipette are very likely to cause issues such as different immersion depths or faulty touch offs of individual tips, leading to negatively impacted pipetting results.

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